| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM89613 |
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| Substrate/Competitor | n/a |
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| IC50 | 3850±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM89613 |
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| n/a |
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| Name | BDBM89613 |
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| Synonyms: | 2-(2-bromophenyl)-5-[[1-(4-methylphenyl)-1,2,3,4-tetrazol-5-yl]sulfanylmethyl]-1,3,4-oxadiazole | 2-(2-bromophenyl)-5-[[1-(4-methylphenyl)tetrazol-5-yl]sulfanylmethyl]-1,3,4-oxadiazole | 2-(2-bromophenyl)-5-[[[1-(4-methylphenyl)-5-tetrazolyl]thio]methyl]-1,3,4-oxadiazole | 2-(2-bromophenyl)-5-[[[1-(p-tolyl)tetrazol-5-yl]thio]methyl]-1,3,4-oxadiazole | MLS000056702 | SMR000065083 | cid_2615763 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13BrN6OS |
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| Mol. Mass. | 429.294 |
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| SMILES | Cc1ccc(cc1)-n1nnnc1SCc1nnc(o1)-c1ccccc1Br |
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| Structure | 
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