| Reaction Details |
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 | Report a problem with these data |
| Target | Xylosyl- and glucuronyltransferase LARGE1 |
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| Ligand | BDBM94714 |
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| Substrate/Competitor | n/a |
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| EC50 | 6370±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of small molecule activators of alpha dystroglycan glycosylation PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Xylosyl- and glucuronyltransferase LARGE1 |
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| Name: | Xylosyl- and glucuronyltransferase LARGE1 |
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| Synonyms: | KIAA0609 | LARG1_HUMAN | LARGE | LARGE1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 88079.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_47678551 |
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| Residue: | 756 |
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| Sequence: | MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQR
ERESLEVRMREVEEENRALRRQLSLAQGRAPSHRRGNHSKTYSMEEGTGDSENLRAGIVA
GNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQ
ILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIV
LDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVI
LLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQL
SDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCP
SEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPAADSTDVTLVAQL
SMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQF
YPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETL
RYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPY
VVVRRDCPEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHAPSFDITKFRSN
KQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS
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| BDBM94714 |
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| n/a |
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| Name | BDBM94714 |
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| Synonyms: | 1-[2-[(4-isobutoxybenzyl)thio]ethyl]-3-phenyl-thiourea | 1-[2-[[4-(2-methylpropoxy)phenyl]methylsulfanyl]ethyl]-3-phenyl-thiourea | 1-[2-[[4-(2-methylpropoxy)phenyl]methylsulfanyl]ethyl]-3-phenylthiourea | 1-[2-[[4-(2-methylpropoxy)phenyl]methylthio]ethyl]-3-phenylthiourea | MLS000574381 | N-{2-[(4-isobutoxybenzyl)thio]ethyl}-N'-phenylthiourea | SMR000195044 | cid_2282785 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H26N2OS2 |
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| Mol. Mass. | 374.563 |
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| SMILES | CC(C)COc1ccc(CSCCNC(=S)Nc2ccccc2)cc1 |
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| Structure | 
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