| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Xylosyl- and glucuronyltransferase LARGE1 |
|---|
| Ligand | BDBM94716 |
|---|
| Substrate/Competitor | n/a |
|---|
| EC50 | 9210±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation of small molecule activators of alpha dystroglycan glycosylation PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Xylosyl- and glucuronyltransferase LARGE1 |
|---|
| Name: | Xylosyl- and glucuronyltransferase LARGE1 |
|---|
| Synonyms: | KIAA0609 | LARG1_HUMAN | LARGE | LARGE1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 88079.63 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_47678551 |
|---|
| Residue: | 756 |
|---|
| Sequence: | MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQR
ERESLEVRMREVEEENRALRRQLSLAQGRAPSHRRGNHSKTYSMEEGTGDSENLRAGIVA
GNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQ
ILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIV
LDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVI
LLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQL
SDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCP
SEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPAADSTDVTLVAQL
SMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQF
YPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETL
RYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPY
VVVRRDCPEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHAPSFDITKFRSN
KQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS
|
|
|
|---|
| BDBM94716 |
|---|
| n/a |
|---|
| Name | BDBM94716 |
|---|
| Synonyms: | (E)-N-[6-(isopropylsulfamoyl)-1,3-benzothiazol-2-yl]-3-(3,4,5-trimethoxyphenyl)acrylamide | (E)-N-[6-(propan-2-ylsulfamoyl)-1,3-benzothiazol-2-yl]-3-(3,4,5-trimethoxyphenyl)-2-propenamide | (E)-N-[6-(propan-2-ylsulfamoyl)-1,3-benzothiazol-2-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamide | MLS000697405 | SMR000238027 | cid_1646845 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H25N3O6S2 |
|---|
| Mol. Mass. | 491.58 |
|---|
| SMILES | COc1cc(\C=C\C(=O)Nc2nc3ccc(cc3s2)S(=O)(=O)NC(C)C)cc(OC)c1OC |
|---|
| Structure | 
|
|---|
Search and Browse
