| Reaction Details |
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 | Report a problem with these data |
| Target | Xylosyl- and glucuronyltransferase LARGE1 |
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| Ligand | BDBM94752 |
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| Substrate/Competitor | n/a |
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| EC50 | 6310±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of small molecule activators of alpha dystroglycan glycosylation PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Xylosyl- and glucuronyltransferase LARGE1 |
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| Name: | Xylosyl- and glucuronyltransferase LARGE1 |
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| Synonyms: | KIAA0609 | LARG1_HUMAN | LARGE | LARGE1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 88079.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_47678551 |
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| Residue: | 756 |
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| Sequence: | MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQR
ERESLEVRMREVEEENRALRRQLSLAQGRAPSHRRGNHSKTYSMEEGTGDSENLRAGIVA
GNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQ
ILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIV
LDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVI
LLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQL
SDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCP
SEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPAADSTDVTLVAQL
SMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQF
YPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETL
RYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPY
VVVRRDCPEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHAPSFDITKFRSN
KQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS
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| BDBM94752 |
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| n/a |
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| Name | BDBM94752 |
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| Synonyms: | (6-bromo-2-p-cumenyl-4-quinolyl)-morpholino-methanone | MLS001125897 | SMR000665492 | [6-bromanyl-2-(4-propan-2-ylphenyl)quinolin-4-yl]-morpholin-4-yl-methanone | [6-bromo-2-(4-propan-2-ylphenyl)-4-quinolinyl]-(4-morpholinyl)methanone | [6-bromo-2-(4-propan-2-ylphenyl)quinolin-4-yl]-morpholin-4-ylmethanone | cid_1226038 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H23BrN2O2 |
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| Mol. Mass. | 439.345 |
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| SMILES | CC(C)c1ccc(cc1)-c1cc(C(=O)N2CCOCC2)c2cc(Br)ccc2n1 |
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| Structure | 
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