| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nuclear receptor subfamily 0 group B member 1 |
|---|
| Ligand | BDBM50012278 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | >67541±n/a nM |
|---|
| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay(2013)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Nuclear receptor subfamily 0 group B member 1 |
|---|
| Name: | Nuclear receptor subfamily 0 group B member 1 |
|---|
| Synonyms: | AHC | DAX1 | NR0B1 | NR0B1_HUMAN |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51729.22 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_5016090 |
|---|
| Residue: | 470 |
|---|
| Sequence: | MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNV
ALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGL
PGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQR
PGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSS
GALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELA
QDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQA
IKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQ
GPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
|
|
|
|---|
| BDBM50012278 |
|---|
| n/a |
|---|
| Name | BDBM50012278 |
|---|
| Synonyms: | (2ALPHA,2''BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE | CHEMBL159 | VINBLASTINE | VINBLASTINE SULFATE | cid_5388983 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C46H58N4O9 |
|---|
| Mol. Mass. | 810.9741 |
|---|
| SMILES | CC[C@]1(O)C[C@@H]2CN(C1)CCc1c([nH]c3ccccc13)[C@@](C2)(C(=O)OC)c1cc2c(cc1OC)N(C)[C@@H]1[C@]22CCN3CC=C[C@](CC)([C@@H]23)[C@@H](OC(C)=O)[C@]1(O)C(=O)OC |r,c:48| |
|---|
| Structure | 
|
|---|
Search and Browse
