| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM280442 |
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| Substrate/Competitor | n/a |
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| EC50 | 2020±n/a nM |
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| Citation |  Livermore, D; White, K; Congreve, M; Brown, G; O Brien, M Piperidin-1-yl and azepin-1-yl carboxylates as muscarinic M4 receptor agonists US Patent US10030012 Publication Date 7/24/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2 |
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| Type: | GPCR |
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| Mol. Mass.: | 51730.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08172 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM280442 |
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| n/a |
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| Name | BDBM280442 |
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| Synonyms: | US10030012, Example 72 | ethyl 4-[4-(6- ethoxypyridin-2- yl)piperidin-1- yl]piperidine-1- carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C20H31N3O3 |
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| Mol. Mass. | 361.4784 |
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| SMILES | CCOC(=O)N1CCC(CC1)N1CCC(CC1)c1cccc(OCC)n1 |
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| Structure | 
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