| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM106370 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radiological Binding Assay |
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| pH | 7.4±0 |
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| Ki | 94±30 nM |
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| Citation |  Borghini, A; Pietra, D; Leonardi, M; Giorgi, I; Bianucci, AM N-[9-(ortho-fluorobenzyl)-2-phenyl-8-azapurin-6-yl]-amides as potent and selective ligands for A1 adenosine receptors. Chem Biol Drug Des82:22-38 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM106370 |
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| n/a |
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| Name | BDBM106370 |
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| Synonyms: | 9-(ortho-fluorobenzyl)-2-phenyl-azaadenine (1bis) |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13FN6 |
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| Mol. Mass. | 320.3237 |
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| SMILES | Nc1nc(nc2n(Cc3ccccc3F)nnc12)-c1ccccc1 |
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| Structure | 
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