Reaction Details |
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Target | Serine/threonine-protein kinase pim-1 |
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Ligand | BDBM108400 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Luminometric Kinase Assay |
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pH | 7±0 |
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IC50 | 14.75±0.0 nM |
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Citation | Brzózka, K; Czardybon, W; Sabiniarz, A; Millik, M; Windak, R; Zarebski, A; Beuzen, N Compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent US Patent US8604217 Publication Date 12/10/2013 |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Serine/threonine-protein kinase pim-1 |
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Name: | Serine/threonine-protein kinase pim-1 |
Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) |
Type: | Protein |
Mol. Mass.: | 35681.82 |
Organism: | Homo sapiens (Human) |
Description: | P11309 |
Residue: | 313 |
Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
EIHLHSLSPGPSK
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BDBM108400 |
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n/a |
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Name | BDBM108400 |
Synonyms: | US8604217, 331 |
Type | Small organic molecule |
Emp. Form. | C13H12Br4N4 |
Mol. Mass. | 543.877 |
SMILES | NC1CC=CCC1Nc1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 |c:3| |
Structure |
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