Reaction Details |
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Target | Fibrinogen beta chain [164-491] |
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Ligand | BDBM38843 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer |
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IC50 | 83293±n/a nM |
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Citation | PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay(2013)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Fibrinogen beta chain [164-491] |
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Name: | Fibrinogen beta chain [164-491] |
Synonyms: | Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 37647.12 |
Organism: | Homo sapiens (Human) |
Description: | gi_28373962 |
Residue: | 328 |
Sequence: | DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYC
RTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGM
FFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDD
GVVWMNWKGSWYSMRKMSMKIRPFFPQQ
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BDBM38843 |
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n/a |
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Name | BDBM38843 |
Synonyms: | (3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolinamine | 3-methylcinnolin-5-amine | MLS000105193 | SMR000055122 | cid_5310645 |
Type | Small organic molecule |
Emp. Form. | C9H9N3 |
Mol. Mass. | 159.1879 |
SMILES | Cc1cc2c(N)cccc2nn1 |
Structure |
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