BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetFibrinogen beta chain [164-491]
LigandBDBM38843
Substrate/Competitorn/a
Meas. Tech.Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer
IC50 83293±n/a nM
Citation PubChem, PC Fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Fibrinogen beta chain [164-491]
Name:Fibrinogen beta chain [164-491]
Synonyms:Chain E, Fragment Double-D From Human Fibrin | FGB | FIBB_HUMAN
Type:Enzyme Catalytic Domain
Mol. Mass.:37647.12
Organism:Homo sapiens (Human)
Description:gi_28373962
Residue:328
Sequence:
DNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYC
RTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQ
NRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIE
MEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGM
FFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDD
GVVWMNWKGSWYSMRKMSMKIRPFFPQQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM38843
n/a
NameBDBM38843
Synonyms:(3-methylcinnolin-5-yl)amine | 3-methyl-5-cinnolinamine | 3-methylcinnolin-5-amine | MLS000105193 | SMR000055122 | cid_5310645
TypeSmall organic molecule
Emp. Form.C9H9N3
Mol. Mass.159.1879
SMILESCc1cc2c(N)cccc2nn1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: