| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nuclear hormone receptor family member daf-12 |
|---|
| Ligand | BDBM114729 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12) |
|---|
| EC50 | 67547±n/a nM |
|---|
| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12) PubChem Bioassay(2013)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Nuclear hormone receptor family member daf-12 |
|---|
| Name: | Nuclear hormone receptor family member daf-12 |
|---|
| Synonyms: | DAF12_CAEEL | Protein DAF-12, isoform a | XL285 | daf-12 | daf-20 | mig-7 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 84211.49 |
|---|
| Organism: | Caenorhabditis elegans |
|---|
| Description: | gi_71987181 |
|---|
| Residue: | 753 |
|---|
| Sequence: | MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQM
STPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRV
CGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFT
VGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYP
PQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLT
MMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLM
NEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIP
GNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAM
IPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQ
MQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGV
TRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAV
YLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALG
LLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK
|
|
|
|---|
| BDBM114729 |
|---|
| n/a |
|---|
| Name | BDBM114729 |
|---|
| Synonyms: | 2,3-dihydro-1,4-benzodioxin-6-yl-(4-phenylthiazol-2-yl)amine;hydrobromide | MLS000569419 | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenyl-1,3-thiazol-2-amine;hydrobromide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenyl-2-thiazolamine;hydrobromide | SMR000155005 | cid_9551891 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H14N2O2S |
|---|
| Mol. Mass. | 310.37 |
|---|
| SMILES | C1COc2cc(Nc3nc(cs3)-c3ccccc3)ccc2O1 |
|---|
| Structure | 
|
|---|
Search and Browse
