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TargetOxysterols receptor LXR-beta
LigandBDBM49454
Substrate/Competitorn/a
Meas. Tech.Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response screening assay to identify agonists of the Liver-X-Receptor (LXR)
EC50 67574±n/a nM
Citation PubChem, PC Counterscreen for agonists of the daf-12 abnormal Dauer Formation: Luminescence-based cell-based dose response screening assay to identify agonists of the Liver-X-Receptor (LXR) PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Oxysterols receptor LXR-beta
Name:Oxysterols receptor LXR-beta
Synonyms:LXRB | Liver X receptor beta (NR1H2) | Liver X, LXR beta | NER | NR1H2 | NR1H2_HUMAN | Nuclear receptor NER | UNR | Ubiquitously-expressed nuclear receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:50978.79
Organism:Homo sapiens (Human)
Description:P55055
Residue:460
Sequence:
MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDW
VIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGA
RRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQ
SQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKR
SFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQI
ALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMR
RLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRM
LMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
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  Blast E-value cutoff:
BDBM49454
n/a
NameBDBM49454
Synonyms:(2Z)-2-(1-anilinoethylidene)-1-benzothiophen-3-one | (2Z)-2-(1-anilinoethylidene)benzothiophen-3-one | (2Z)-2-(1-phenylazanylethylidene)-1-benzothiophen-3-one | 2-[1-Phenylamino-eth-(Z)-ylidene]-benzo[b]thiophen-3-one | MLS000550925 | SMR000145053 | cid_5399972
TypeSmall organic molecule
Emp. Form.C16H13NOS
Mol. Mass.267.346
SMILESCC(=Nc1ccccc1)c1sc2ccccc2c1O |w:2.2|
Structure
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