| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 12 |
|---|
| Ligand | BDBM124970 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Kinase Screen Assay |
|---|
| Kd | 100±n/a nM |
|---|
| Citation |  Choi, HG; Sim, T; Gray, N; Zhou, W; Chang, JW; Zhang, J; Weisberg, E Fused 2-aminothiazole compounds US Patent US8765747 Publication Date 7/1/2014 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mitogen-activated protein kinase 12 |
|---|
| Name: | Mitogen-activated protein kinase 12 |
|---|
| Synonyms: | ERK6 | MAP kinase p38 gamma | MAPK12 | MK12_HUMAN | Mitogen-activated protein kinase 12 (MAPK12 p38 gamma) | Mitogen-activated protein kinase 12 (p38 gamma) | Mitogen-activated protein kinase 12 Gamma | Mitogen-activated protein kinase p38 gamma (p38 MAPKγ) | SAPK3 | p38 delta/gamma |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 41938.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P53778 |
|---|
| Residue: | 367 |
|---|
| Sequence: | MSSPPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRV
TAGEALAHPYFESLHDTEDEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAR
VSKETPL
|
|
|
|---|
| BDBM124970 |
|---|
| n/a |
|---|
| Name | BDBM124970 |
|---|
| Synonyms: | US8765747, 2 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H31F3N6O2S |
|---|
| Mol. Mass. | 608.677 |
|---|
| SMILES | CCN1CCN(Cc2ccc(NC(=O)c3cccc(c3)-c3ccc4nc(NC(=O)C5CC5)sc4n3)cc2C(F)(F)F)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
