Reaction Details | |||
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Target | C-C chemokine receptor type 2 | ||
Ligand | BDBM141914 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Binding Assay | ||
Temperature | 310.15±n/a K | ||
IC50 | 13±n/a nM | ||
Comments | extracted | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
C-C chemokine receptor type 2 | |||
Name: | C-C chemokine receptor type 2 | ||
Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) | ||
Type: | Enzyme | ||
Mol. Mass.: | 41932.32 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P41597 | ||
Residue: | 374 | ||
Sequence: |
| ||
BDBM141914 | |||
n/a | |||
Name | BDBM141914 | ||
Synonyms: | US8921559, 1a | US8921559, 1b | US8921559, 2b | ||
Type | Small organic molecule | ||
Emp. Form. | C30H34F2N4O2 | ||
Mol. Mass. | 520.6134 | ||
SMILES | NC(=O)C(N[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)\C=C\c1cc(F)cc(F)c1 |r,wU:5.4,wD:8.11,(-.82,1.19,;-2.15,.42,;-3.48,1.19,;-2.15,-1.12,;-3.48,-1.89,;-4.82,-1.12,;-6.15,-1.89,;-7.48,-1.12,;-7.48,.42,;-6.15,1.19,;-4.82,.42,;-8.82,1.19,;-10.28,.71,;-11.19,1.96,;-10.28,3.2,;-10.6,4.71,;-9.46,5.74,;-7.99,5.27,;-7.67,3.76,;-8.82,2.73,;-.82,-1.89,;-.82,-3.43,;.52,-4.2,;1.85,-3.43,;1.85,-1.89,;.52,-1.12,;3.19,-4.2,;3.19,-5.74,;4.52,-3.43,;5.85,-4.2,;7.19,-3.43,;8.52,-4.2,;9.85,-3.43,;11.19,-4.2,;9.85,-1.89,;8.52,-1.12,;8.52,.42,;7.19,-1.89,)| | ||
Structure | ![]() |