Reaction Details | |||
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Target | C-C chemokine receptor type 2 | ||
Ligand | BDBM141924 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Binding Assay | ||
Temperature | 310.15±n/a K | ||
IC50 | 150±n/a nM | ||
Comments | extracted | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
C-C chemokine receptor type 2 | |||
Name: | C-C chemokine receptor type 2 | ||
Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) | ||
Type: | Enzyme | ||
Mol. Mass.: | 41932.32 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P41597 | ||
Residue: | 374 | ||
Sequence: |
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BDBM141924 | |||
n/a | |||
Name | BDBM141924 | ||
Synonyms: | US8921559, 16 | ||
Type | Small organic molecule | ||
Emp. Form. | C29H34F3N5O2 | ||
Mol. Mass. | 541.6078 | ||
SMILES | NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)Nc1cccc(c1)C(F)(F)F |(-.82,1.57,;-2.15,.8,;-3.48,1.57,;-2.15,-.74,;-3.48,-1.51,;-4.82,-.74,;-6.15,-1.51,;-7.48,-.74,;-7.48,.8,;-6.15,1.57,;-4.82,.8,;-8.82,1.57,;-10.28,1.1,;-11.19,2.34,;-10.28,3.59,;-10.6,5.1,;-9.46,6.13,;-7.99,5.65,;-7.67,4.14,;-8.82,3.11,;-.82,-1.51,;-.82,-3.05,;.52,-3.82,;1.85,-3.05,;1.85,-1.51,;.52,-.74,;3.19,-3.82,;3.19,-5.36,;4.52,-3.05,;5.85,-3.82,;5.85,-5.36,;7.19,-6.13,;8.52,-5.36,;8.52,-3.82,;7.19,-3.05,;9.85,-3.05,;11.19,-3.82,;9.85,-1.51,;11.19,-2.28,)| | ||
Structure | ![]() |