| Reaction Details |
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 | Report a problem with these data |
| Target | Androgen receptor |
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| Ligand | BDBM144728 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Androgen Receptor Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 11±4.00 nM |
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| Comments | extracted |
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| Citation |  Labrie, F; Singh, SM; Labrecque, R; Ciobanu, LC Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety US Patent US9682960 Publication Date 6/20/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Androgen receptor |
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| Name: | Androgen receptor |
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| Synonyms: | ANDR_MOUSE | Ar | Nr3c4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 98196.62 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_945930 |
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| Residue: | 899 |
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| Sequence: | MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREAIQNPGPRHPEAANIAPPGACLQQRQET
SPRRRRRQQHTEDGSPQAHIRGPTGYLALEEEQQPSQQQAASEGHPESSCLPEPGAATAP
GKGLPQQPPAPPDQDDSAAPSTLSLLGPTFPGLSSCSADIKDILNEAGTMQLLQQQQQQQ
QHQQQHQQHQQQQEVISEGSSARAREATGAPSSSKDSYLGGNSTISDSAKELCKAVSVSM
GLGVEALEHLSPGEQLRGDCMYASLLGGPPAVRPTPCAPLPECKGLPLDEGPGKSTEETA
EYSSFKGGYAKGLEGESLGCSGSSEAGSSGTLEIPSSLSLYKSGALDEAAAYQNRDYYNF
PLALSGPPHPPPPTHPHARIKLENPLDYGSAWAAAAAQCRYGDLGSLHGGSVAGPSTGSP
PATTSSSWHTLFTAEEGQLYGPGGGGGSSSPSDAGPVAPYGYTRPPQGLTSQESDYSASE
VWYPGGVVNRVPYPSPNCVKSEMGPWMENYSGPYGDMRLDSTRDHVLPIDYYFPPQKTCL
ICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCY
EAGMTLGARKLKKLGNLKLQEEGENSNAGSPTEDPSQKMTVSHIEGYECQPIFLNVLEAI
EPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYS
WMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQIT
PQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLT
KLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
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| BDBM144728 |
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| n/a |
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| Name | BDBM144728 |
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| Synonyms: | US9682960, EM-9066 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H22F4N4O3 |
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| Mol. Mass. | 526.4822 |
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| SMILES | CC1(C)N(CCCOc2ccc(c(F)c2)-c2ccncc2)C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F |
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| Structure | 
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