| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform 2 of Protein mono-ADP-ribosyltransferase PARP3 (Long) |
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| Ligand | BDBM207588 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PARP-2 and PARP-3 Enzymatic Assay |
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| IC50 | 11000±n/a nM |
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| Citation |  Zhou, C; Ren, B; Wang, H Fused tetra or penta-cyclic dihydrodiazepinocarbazolones as PARP inhibitors US Patent US9260440 Publication Date 2/16/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Isoform 2 of Protein mono-ADP-ribosyltransferase PARP3 (Long) |
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| Name: | Isoform 2 of Protein mono-ADP-ribosyltransferase PARP3 (Long) |
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| Synonyms: | ADPRT3 | ADPRTL3 | PARP3 | PARP3_HUMAN | Poly [ADP-ribose] polymerase 3 (PARP-3) | Protein mono-ADP-ribosyltransferase PARP3 (Long) |
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| Type: | Protein |
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| Mol. Mass.: | 60847.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y6F1-2 |
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| Residue: | 540 |
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| Sequence: | MSLLFLAMAPKPKPWVQTEGPEKKKGRQAGREEDPFRSTAEALKAIPAEKRIIRVDPTCP
LSSNPGTQVYEDYNCTLNQTNIENNNNKFYIIQLLQDSNRFFTCWNHWGRVGEVGQSKIN
HFTRLEDAKKDFEKKFREKTKNNWAERDHFVSHPGKYTLIEVQAEDEAQEAVVKVDRGPV
RTVTKRVQPCSLDPATQKLITNIFSKEMFKNTMALMDLDVKKMPLGKLSKQQIARGFEAL
EALEEALKGPTDGGQSLEELSSHFYTVIPHNFGHSQPPPINSPELLQAKKDMLLVLADIE
LAQALQAVSEQEKTVEEVPHPLDRDYQLLKCQLQLLDSGAPEYKVIQTYLEQTGSNHRCP
TLQHIWKVNQEGEEDRFQAHSKLGNRKLLWHGTNMAVVAAILTSGLRIMPHSGGRVGKGI
YFASENSKSAGYVIGMKCGAHHVGYMFLGEVALGREHHINTDNPSLKSPPPGFDSVIARG
HTEPDPTQDTELELDGQQVVVPQGQPVPCPEFSSSTFSQSEYLIYQESQCRLRYLLEVHL
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| BDBM207588 |
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| n/a |
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| Name | BDBM207588 |
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| Synonyms: | US10501467, Example 33 | US9260440, 33 | US9617273, Example 33 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H28N4O |
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| Mol. Mass. | 352.4732 |
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| SMILES | CCN(CC)CCn1c2CC(C)(C)Cc3n[nH]c(=O)c4cccc1c4c23 |
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| Structure | 
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