| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Egl nine homolog 1 [179-426] |
|---|
| Ligand | BDBM126621 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Activity Assay |
|---|
| pH | 7.5±n/a |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | 9000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Shalwitz, R; Gardner, JH Methods for increasing the stabilization of hypoxia inducible factor-α US Patent US9278930 Publication Date 3/8/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Egl nine homolog 1 [179-426] |
|---|
| Name: | Egl nine homolog 1 [179-426] |
|---|
| Synonyms: | C1orf12 | EGLN1 | EGLN1_HUMAN | Hypoxia-inducible factor prolyl hydroxylase 2 (HIFPH2) |
|---|
| Type: | n/a |
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| Mol. Mass.: | 27759.84 |
|---|
| Organism: | Homo sapiens (Human) |
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| Description: | EGLN-1-179/426 |
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| Residue: | 248 |
|---|
| Sequence: | LRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDG
QLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKA
MVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEP
KFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPS
DSVGKDVF
|
|
|
|---|
| BDBM126621 |
|---|
| n/a |
|---|
| Name | BDBM126621 |
|---|
| Synonyms: | US10562854, No. B5 | US8778412, B5 | US9278930, B5 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H24N2O3 |
|---|
| Mol. Mass. | 328.4055 |
|---|
| SMILES | OCC[C@H]1CCCN1Cc1ccn(Cc2ccccc2)c(=O)c1O |r| |
|---|
| Structure | 
|
|---|
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