Reaction Details |
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Target | E3 ubiquitin-protein ligase XIAP [241-356] |
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Ligand | BDBM213393 |
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Substrate/Competitor | n/a |
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Meas. Tech. | XIAP BIR3 & cIAP1 BIR3 Binding Assays (DELFIA) |
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Temperature | 298.15±n/a K |
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IC50 | 350±n/a nM |
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Comments | extracted |
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Citation | Reiser, U; Madden, J 6-Alkynyl Pyridine US Patent US9278978 Publication Date 3/8/2016 |
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More Info.: | Get all data from this article, Assay Method |
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E3 ubiquitin-protein ligase XIAP [241-356] |
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Name: | E3 ubiquitin-protein ligase XIAP [241-356] |
Synonyms: | API3 | BIR3 domain of X-linked inhibitor of apoptosis protein | BIRC4 | E3 ubiquitin-protein ligase (XIAP-BIR3) | E3 ubiquitin-protein ligase XIAP BIR-3 | E3 ubiquitin-protein ligase XIAP BIR3 | IAP3 | X chromosome-linked inhibitor of apoptosis BIR3 domain (XIAP BIR3) | X-linked inhibitor of apoptosis protein BIR3 domain (XIAP BIR-3) | XIAP | XIAP-BIR3 | XIAP_HUMAN | baculovirus IAP repeat 3 (BIR3) domain of XIAP |
Type: | Protein Binding Domain |
Mol. Mass.: | 13276.62 |
Organism: | Homo sapiens (Human) |
Description: | BIR3 of XIAP: RESIDUES 241-356. |
Residue: | 116 |
Sequence: | SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC
FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT
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BDBM213393 |
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n/a |
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Name | BDBM213393 |
Synonyms: | US9278978, 28 |
Type | Small organic molecule |
Emp. Form. | C22H20N4O |
Mol. Mass. | 356.4204 |
SMILES | CN[C@H](C)C(=O)Nc1cc(cc(n1)C#Cc1ccccc1)-c1ccncc1 |r| |
Structure |
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