Reaction Details |
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Target | Baculoviral IAP repeat-containing protein 2 [256-363] |
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Ligand | BDBM213375 |
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Substrate/Competitor | n/a |
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Meas. Tech. | XIAP BIR3 & cIAP1 BIR3 Binding Assays (DELFIA) |
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Temperature | 298.15±n/a K |
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IC50 | 2±n/a nM |
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Comments | extracted |
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Citation | Reiser, U; Madden, J 6-Alkynyl Pyridine US Patent US9278978 Publication Date 3/8/2016 |
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More Info.: | Get all data from this article, Assay Method |
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Baculoviral IAP repeat-containing protein 2 [256-363] |
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Name: | Baculoviral IAP repeat-containing protein 2 [256-363] |
Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | Cellular inhibitor of apoptosis 1 (c-IAP1/BIR3) | Cellular inhibitor of apoptosis 1 BIR3 domain (c-IAP1 BIR3) | IAP repeat-containing protein 2 (cIAP1) BIR-3 | MIHB | RNF48 |
Type: | Enzyme |
Mol. Mass.: | 12600.71 |
Organism: | Homo sapiens (Human) |
Description: | Human cIAP BIR3 domain (256-363 aa) |
Residue: | 108 |
Sequence: | TLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRC
WESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTS
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BDBM213375 |
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n/a |
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Name | BDBM213375 |
Synonyms: | US9278978, 10 |
Type | Small organic molecule |
Emp. Form. | C25H23N5O2 |
Mol. Mass. | 425.4824 |
SMILES | CN[C@H](C)C(=O)Nc1cc(cc(n1)C#Cc1ccccc1)-c1ncnc2oc(C)c(C)c12 |r| |
Structure |
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