| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase II subunit beta |
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| Ligand | BDBM219752 |
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| Substrate/Competitor | BDBM220103 |
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| Meas. Tech. | Inhibition Assay |
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| pH | 7±n/a |
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| IC50 | 65249±n/a nM |
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| Comments | extracted |
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| Citation |  Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM Pyrazolopyrimidines and related heterocycles as CK2 inhibitors US Patent US9303033 Publication Date 4/5/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase II subunit beta |
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| Name: | Casein kinase II subunit beta |
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| Synonyms: | CK2N | CSK2B_HUMAN | CSNK2B | Casein kinase II subunit beta | Casein kinase II subunit beta (CK2 beta) | Casein kinase II subunit beta (CK2β) | G5A | Serine/threonine-protein kinase pim-2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 24937.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P67870 |
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| Residue: | 215 |
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| Sequence: | MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDE
ELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPML
PIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPA
NQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR
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| BDBM219752 |
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| BDBM220103 |
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| Name | BDBM219752 |
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| Synonyms: | US9303033, B48, Table 58A, Compound 25 | US9303033, H49, Table 59A, Compound 18 | US9303033, K36, Table 39A, Compound 59 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29N9O3 |
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| Mol. Mass. | 503.5563 |
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| SMILES | CC(C)N1CCN(CC1)c1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 |
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| Structure | 
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