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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine-protein kinase ATM | ||
| Ligand | BDBM245510 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Cellular Assay | ||
| Temperature | 310.15±n/a K | ||
| IC50 | 0.292±n/a nM | ||
| Comments | extracted | ||
| Citation |  Barlaam, BC; Pike, KG Imidazo[4,5-c]quinolin-2-one compounds and their use in treating Cancer US Patent US9428503 Publication Date 8/30/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Serine-protein kinase ATM | |||
| Name: | Serine-protein kinase ATM | ||
| Synonyms: | A-T mutated | ATM | ATM_HUMAN | Ataxia telangiectasia mutated | ||
| Type: | Protein | ||
| Mol. Mass.: | 350696.72 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q13315 | ||
| Residue: | 3056 | ||
| Sequence: |
| ||
| BDBM245510 | |||
| n/a | |||
| Name | BDBM245510 | ||
| Synonyms: | US9428503, 38 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H31N5O3 | ||
| Mol. Mass. | 473.5667 | ||
| SMILES | CO[C@H]1C[C@H](C1)n1c2c(cnc3ccc(cc23)-c2ccc(OCCCN3CCC3)nc2)n(C)c1=O |r,wD:4.6,2.1,(3.37,4.9,;2.97,3.41,;4.06,2.32,;4.06,.78,;5.6,.78,;5.6,2.32,;6.69,-.31,;6.37,-1.82,;7.71,-2.59,;7.71,-4.13,;6.37,-4.9,;5.04,-4.13,;3.7,-4.9,;2.37,-4.13,;2.37,-2.59,;3.7,-1.82,;5.04,-2.59,;1.04,-1.82,;1.04,-.28,;-.3,.49,;-1.63,-.28,;-2.96,.49,;-4.3,-.28,;-5.63,.49,;-6.96,-.28,;-8.3,.49,;-8.7,1.98,;-10.18,1.58,;-9.79,.1,;-1.63,-1.82,;-.3,-2.59,;8.85,-1.56,;10.18,-2.33,;8.22,-.15,;8.99,1.19,)| | ||
| Structure | 
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