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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Bifunctional epoxide hydrolase 2 | ||
| Ligand | BDBM25739 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| IC50 | 8.00±n/a nM | ||
| Citation |  Guedes, AG; Hammock, BD; Morisseau, C Treatment of inflammatory disorders in non-human mammals US Patent US10383835 Publication Date 8/20/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Bifunctional epoxide hydrolase 2 | |||
| Name: | Bifunctional epoxide hydrolase 2 | ||
| Synonyms: | EPHX2 | HYES_PIG | Soluble Epoxide Hydrolase | ||
| Type: | n/a | ||
| Mol. Mass.: | 62766.18 | ||
| Organism: | Sus scrofa (Pig) | ||
| Description: | Q6Q2C2 | ||
| Residue: | 555 | ||
| Sequence: |
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| BDBM25739 | |||
| n/a | |||
| Name | BDBM25739 | ||
| Synonyms: | 4-({4-[(adamantan-1-ylcarbamoyl)amino]cyclohexyl}oxy)benzoic acid | US10383835, Compound 1471 | Urea-based compound, 20 | Urea-based compound, 21 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H32N2O4 | ||
| Mol. Mass. | 412.5219 | ||
| SMILES | OC(=O)c1ccc(OC2CCC(CC2)NC(=O)NC23CC4CC(CC(C4)C2)C3)cc1 |TLB:25:20:27:24.23.26,25:24:20.21.19:27,THB:23:22:19:24.25.26,23:24:19:22.21.27,(14.72,-2.13,;14.72,-.59,;16.06,.18,;13.39,.18,;13.39,1.72,;12.06,2.49,;10.72,1.72,;9.24,2.11,;7.9,1.34,;6.86,2.47,;5.01,1.58,;3.75,1.86,;4.78,.7,;6.61,1.63,;2.42,1.09,;1.08,1.86,;1.08,3.4,;-.25,1.08,;-1.58,1.85,;-1.14,3.3,;-2.2,4.45,;-3.36,3.57,;-3.92,1.7,;-5.24,1.54,;-4.25,2.53,;-3.76,4.14,;-3.03,1.56,;-2.63,.75,;10.72,.18,;12.06,-.59,)| | ||
| Structure | 
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