| Reaction Details |
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 | Report a problem with these data |
| Target | E3 ubiquitin-protein ligase ORTHRUS 5 |
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| Ligand | BDBM426630 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | beta-lactamase assay |
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| Ki | 15570±n/a nM |
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| Citation |  Chen, Y; Pemberton, OA; Renslo, A; Jaishankar, P Beta-lactamase inhibitors, formulations, and uses thereof US Patent US10543221 Publication Date 1/28/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| E3 ubiquitin-protein ligase ORTHRUS 5 |
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| Name: | E3 ubiquitin-protein ligase ORTHRUS 5 |
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| Synonyms: | ORTH5 | ORTH5_ARATH | Protein VARIANT IN METHYLATION 2 | RING-type E3 ubiquitin transferase ORTHRUS 5 | VIM2 |
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| Type: | Protein |
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| Mol. Mass.: | 68730.62 |
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| Organism: | Mouse-ear cress |
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| Description: | Q680I0 |
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| Residue: | 623 |
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| Sequence: | MAIQTQLPCDGDGVCMRCQVNPPSEETLTCGTCVTPWHVSCLLPESLASSTGDWECPDCS
GVVVPSAAPGTGISGPESSGSVLVTAIRAIQADVTLTEAEKAKKRQRLMSGGGDDGVDDE
EKKKLEIFCSICIQLPERPVTTPCGHNFCLKCFEKWAVGQGKLTCMICRSKIPRHVAKNP
RINLALVSAIRLANVTKCSGEATAAKVHHIIRNQDRPDKAFTTERAVKTGKANAASGKFF
VTIPRDHFGPIPAANDVTRNQGVLVGESWEDRQECRQWGVHFPHVAGIAGQAAVGAQSVA
LSGGYDDDEDHGEWFLYTGSGGRDLSGNKRVNKIQSSDQAFKNMNEALRLSCKMGYPVRV
VRSWKEKRSAYAPAEGVRYDGVYRIEKCWSNVGVQGLHKMCRYLFVRCDNEPAPWTSDEH
GDRPRPLPDVPELENATDLFVRKESPSWGFDEAEGRWKWMKSPPVSRMALDTEERKKNKR
AKKGNNAMKARLLKEFSCQICRKVLSLPVTTPCAHNFCKACLEAKFAGITQLRDRSNGVR
KLRAKKNIMTCPCCTTDLSEFLQNPQVNREMMEIIENFKKSEEEAEVAESSNISEEEGEE
ESEPPTKKIKMDKNSVGGTSLSA
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| BDBM426630 |
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| n/a |
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| Name | BDBM426630 |
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| Synonyms: | US10543221, Compound 995018 | US10543221, Formula 16 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H12NO4P |
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| Mol. Mass. | 253.191 |
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| SMILES | Cn1c2ccccc2c(CP(O)(O)=O)cc1=O |
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| Structure | 
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