| Reaction Details |
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 | Report a problem with these data |
| Target | Proteasome subunit beta type-1 |
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| Ligand | BDBM441784 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Proteasome-Activity Inhibitory Assay |
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| IC50 | >20000±n/a nM |
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| Citation |  Yang, J; Cen, JJ; Fan, XM Epoxyketone compounds for enzyme inhibition US Patent US10640533 Publication Date 5/5/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Proteasome subunit beta type-1 |
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| Name: | Proteasome subunit beta type-1 |
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| Synonyms: | PSB1_HUMAN | PSC5 | PSMB1 | Proteasome component C5 | Proteasome subunit beta type-1/beta type-5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26493.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1366691 |
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| Residue: | 241 |
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| Sequence: | MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEG
FSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAML
STILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQ
VGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRK
D
|
|
|
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| BDBM441784 |
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| n/a |
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| Name | BDBM441784 |
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| Synonyms: | US10640533, Identification number CX13-600 | US10640533, Table 1.31 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H47N5O7 |
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| Mol. Mass. | 673.7984 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)c1cc(CN2CCOCC2)on1)C(=O)[C@@]1(C)CO1 |r| |
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| Structure | 
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