| Reaction Details |
|---|
 | Report a problem with these data |
| Target | fMet-Leu-Phe receptor |
|---|
| Ligand | BDBM454192 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | cAMP Assay |
|---|
| EC50 | 32.0±n/a nM |
|---|
| Citation |  Wurtz, NR; Shirude, PS Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists US Patent US10717708 Publication Date 7/21/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| fMet-Leu-Phe receptor |
|---|
| Name: | fMet-Leu-Phe receptor |
|---|
| Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 38456.14 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_4503779 |
|---|
| Residue: | 350 |
|---|
| Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
|
|
|
|---|
| BDBM454192 |
|---|
| n/a |
|---|
| Name | BDBM454192 |
|---|
| Synonyms: | US10717708, Example 86 | US11186544, Example 86 | US11530183, Example 86 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H25ClN4O4S |
|---|
| Mol. Mass. | 513.008 |
|---|
| SMILES | CS(=O)(=O)Nc1ccccc1-c1ccc(cc1)N1CCC[C@@H](NC(=O)Nc2ccc(Cl)cc2)C1=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
