| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM457877 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | radioligand binding assay |
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| Ki | 550±n/a nM |
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| Citation |  Holson, E; Fevrier, F; Weiwer, M; Scolnick, E; Palmer, M; Lewis, MC; Pan, JQ; Zhang, Y; Xu, Q Dopamine D2 receptor ligands US Patent US10752588 Publication Date 8/25/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM457877 |
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| n/a |
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| Name | BDBM457877 |
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| Synonyms: | US10752588, Compound 25 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28FN3O2 |
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| Mol. Mass. | 433.5178 |
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| SMILES | Fc1ccc(cc1)C(NC(=O)C1CCN(CCOc2ccccc2)CC1)c1ccccn1 |
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| Structure | 
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