| Reaction Details |
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 | Report a problem with these data |
| Target | HIV-1 protease |
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| Ligand | BDBM468564 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Inhibition of Purified HIV-1 Protease |
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| IC50 | 0.358±n/a nM |
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| Citation |  Jude-Fishburn, CS; VanderVeen, LA; Riley, TA Protease inhibitors having enhanced features US Patent US10806794 Publication Date 10/20/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| HIV-1 protease |
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| Name: | HIV-1 protease |
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| Synonyms: | HIV-1 protease wild type |
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| Type: | Protein |
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| Mol. Mass.: | 10757.68 |
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| Organism: | Human immunodeficiency virus |
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| Description: | O90785 |
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| Residue: | 99 |
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| Sequence: | PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE
QVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF
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| BDBM468564 |
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| n/a |
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| Name | BDBM468564 |
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| Synonyms: | US10806794, Compound mPEG7-O-Darunavir |
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| Type | Small organic molecule |
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| Emp. Form. | C42H67N3O15S |
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| Mol. Mass. | 886.057 |
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| SMILES | COCCOCCOCCOCCOCCOCCOCCOc1ccc(C[C@H](NC(=O)O[C@H]2CO[C@H]3OCC[C@@H]23)C(O)CN(CC(C)C)S(=O)(=O)c2ccc(N)cc2)cc1 |r| |
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| Structure | 
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