| Reaction Details |
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 | Report a problem with these data |
| Target | Histone acetyltransferase KAT5 Isoform 2 [2-461] |
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| Ligand | BDBM653590 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Acetyltransferase Biochemical Assay |
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| IC50 | 867±n/a nM |
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| Citation |  Stupple, PA; Lagiakos, HR; Foitzik, RC; Camerino, MA; Nikolakopoulos, G; Bozikis, YE; Kersten, WJ; Walker, SR; Hubert, JG Compounds US Patent US11911372 Publication Date 2/27/2024 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone acetyltransferase KAT5 Isoform 2 [2-461] |
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| Name: | Histone acetyltransferase KAT5 |
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| Synonyms: | HTATIP | KAT5 | KAT5_HUMAN | TIP60 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58595.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_796787 |
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| Residue: | 513 |
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| Sequence: | MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH
ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPK
EREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAV
AAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRH
RLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTIS
FFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKE
STEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ
TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDI
VDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
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| BDBM653590 |
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| n/a |
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| Name | BDBM653590 |
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| Synonyms: | US11911372, Example 11 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22N2O6S |
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| Mol. Mass. | 466.506 |
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| SMILES | COc1ccccc1-c1cc(NS(=O)(=O)c2c(OC)cc(cc2OC)-c2ccccc2)no1 |
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| Structure | 
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