Reaction Details | |||
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Target | Tyrosine-protein kinase SYK | ||
Ligand | BDBM302011 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Homogeneous Time-Resolved Fluorescence (HTRF) Assay | ||
IC50 | 1.84±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Tyrosine-protein kinase SYK | |||
Name: | Tyrosine-protein kinase SYK | ||
Synonyms: | KSYK_HUMAN | SYK | Spleen Tyrosine Kinase | Spleen tyrosine kinase (SYK) | Tyrosine-protein kinase SYK (Syk) | ||
Type: | Enzyme | ||
Mol. Mass.: | 72079.99 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P43405 | ||
Residue: | 635 | ||
Sequence: |
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BDBM302011 | |||
n/a | |||
Name | BDBM302011 | ||
Synonyms: | US9598405, 2.10 | ||
Type | Small Organic Molecule | ||
Emp. Form. | C25H28N4O5S | ||
Mol. Mass. | 496.579 | ||
SMILES | CCOC(=O)C1CCC(O)(CC1)c1ncc(s1)-c1cc(C)cc(Nc2cc(ccn2)C(=O)OC)n1 |(-7.3,.16,;-5.76,.1,;-5.04,-1.26,;-3.5,-1.31,;-2.69,-0,;-2.78,-2.67,;-1.24,-2.72,;-.52,-4.08,;-1.33,-5.39,;-.06,-6.25,;-2.87,-5.34,;-3.6,-3.98,;-1.33,-6.93,;-2.58,-7.84,;-2.1,-9.3,;-.56,-9.3,;-.09,-7.84,;.34,-10.55,;1.87,-10.38,;2.78,-11.63,;4.31,-11.47,;2.15,-13.04,;.62,-13.2,;-.01,-14.61,;.9,-15.85,;.27,-17.26,;1.18,-18.5,;2.71,-18.34,;3.34,-16.94,;2.43,-15.69,;.55,-19.91,;-.98,-20.07,;1.46,-21.16,;2.99,-21,;-.28,-11.95,)| | ||
Structure | ![]() |