| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 2/Small ubiquitin-related modifier 1 |
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| Ligand | BDBM103832 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Kinetic Assay |
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| IC50 | >60000±n/a nM |
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| Citation |  Chen, Y; Chen, C; Namanja, A Methods of identifying SENP1 inhibitors US Patent US11041859 Publication Date 6/22/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Sentrin-specific protease 2/Small ubiquitin-related modifier 1 |
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| Name: | Sentrin-specific protease 2/Small ubiquitin-related modifier 1 |
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| Synonyms: | SUMO1/SENP2 |
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| Type: | Protein |
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| Mol. Mass.: | n/a |
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| Description: | n/a |
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| Components: | This complex has 2 components. |
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| Component 1 |
| Name: | Small ubiquitin-related modifier 1 |
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| Synonyms: | SMT3C | SMT3H3 | SUMO1 | SUMO1_HUMAN | Small ubiquitin-related modifier 1 | UBL1 |
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| Type: | Protein |
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| Mol. Mass.: | 11553.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 101 |
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| Sequence: | MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMN
SLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV
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| Component 2 |
| Name: | Sentrin-specific protease 2 |
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| Synonyms: | KIAA1331 | SENP2 | SENP2_HUMAN | Sentrin-specific protease 2 (SENP2) |
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| Type: | Protein |
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| Mol. Mass.: | 67890.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9HC62 |
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| Residue: | 589 |
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| Sequence: | MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVK
NSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLG
NKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKP
QEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYH
SSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTE
TMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDR
RTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYM
NLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWS
LVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIP
QQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL
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| BDBM103832 |
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| n/a |
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| Name | BDBM103832 |
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| Synonyms: | SPI-07 | US11041859, Code SPI-07 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13N3O6S2 |
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| Mol. Mass. | 419.433 |
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| SMILES | Cc1cc(N)ccc1\N=N\c1cc(c2cccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O |
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| Structure | 
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