| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase |
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| Ligand | BDBM50204290 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radiometric Protein Kinase Assay |
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| IC50 | 4620±n/a nM |
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| Citation |  Griebenow, N; Mottier, MD; Beddies, G; Cramer, J; Bömer, U; Heisler, I Use of fused heteroaromatic pyrrolidones for treatment and prevention of diseases in animals US Patent US11077111 Publication Date 8/3/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase |
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| Name: | Tyrosine-protein kinase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 71935.37 |
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| Organism: | Dog |
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| Description: | A0A3Q7SEB1 |
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| Residue: | 633 |
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| Sequence: | MAGSMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA
HHYTIEREMNGTYAIAGGRTHGSPAELCHYHSQESDGLVCLLKQPFHRPPGVQPKTGPFE
DLKESLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRVESEQI
VMIGSKTNGKFLIRDRNDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGGQPGNINFGARAPLPGAHPATWSAGGIISRIKSYTFPK
PGHRKAASSTGSRPESSFNPYEPDRGPWATDRDAQREALPMDTEVYESPYADPEEIRPKE
VYLDRKLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEAN
VMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGM
KYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPE
CINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPAGCPREMY
ELMKLCWTYEVDRRPGFEAVELRLRNYYYDVVN
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| BDBM50204290 |
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| n/a |
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| Name | BDBM50204290 |
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| Synonyms: | CHEMBL3979920 | US11077111, Compound IIIa | US20230295171, Example 102 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21FN6O |
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| Mol. Mass. | 344.3866 |
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| SMILES | Cn1cc(cn1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(F)c2CNC(=O)c12 |r| |
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| Structure | 
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