| Reaction Details |
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 | Report a problem with these data |
| Target | Pantetheinase [22-493] |
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| Ligand | BDBM510519 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| IC50 | 0.300±n/a nM |
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| Citation |  Fleck, MT; Godbout, C; Koolman, HF Heteroaromatic compounds as Vanin inhibitors US Patent US11078182 Publication Date 8/3/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Pantetheinase [22-493] |
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| Name: | Pantetheinase [22-493] |
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| Synonyms: | Pantetheinase (VNN1)(22-493) | VNN1 | VNN1_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52490.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | aa 22-493 |
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| Residue: | 472 |
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| Sequence: | QDTFTAAVYEHAAILPNATLTPVSREEALALMNRNLDILEGAITSAADQGAHIIVTPEDA
IYGWNFNRDSLYPYLEDIPDPEVNWIPCNNRNRFGQTPVQERLSCLAKNNSIYVVANIGD
KKPCDTSDPQCPPDGRYQYNTDVVFDSQGKLVARYHKQNLFMGENQFNVPKEPEIVTFNT
TFGSFGIFTCFDILFHDPAVTLVKDFHVDTIVFPTAWMNVLPHLSAVEFHSAWAMGMRVN
FLASNIHYPSKKMTGSGIYAPNSSRAFHYDMKTEEGKLLLSQLDSHPSHSAVVNWTSYAS
SIEALSSGNKEFKGTVFFDEFTFVKLTGVAGNYTVCQKDLCCHLSYKMSENIPNEVYALG
AFDGLHTVEGRYYLQICTLLKCKTTNLNTCGDSAETASTRFEMFSLSGTFGTQYVFPEVL
LSENQLAPGEFQVSTDGRLFSLKPTSGPVLTVTLFGRLYEKDWASNASSGLT
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| BDBM510519 |
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| n/a |
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| Name | BDBM510519 |
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| Synonyms: | US11078182, Ex. 1.5 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H28N4O2 |
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| Mol. Mass. | 344.4512 |
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| SMILES | CN([C@H]1CCN(C1)C(=O)c1ccc(NC(C)(C)C)nc1)C(=O)C1CC1 |r| |
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| Structure | 
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