Reaction Details |
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Target | E3 ubiquitin-protein ligase XIAP [265-330] |
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Ligand | BDBM518275 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Biological Assay |
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Ki | <25000±n/a nM |
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Citation | Cosford, ND; Vamos, MD Inhibitor of apoptosis protein (IAP) antagonists US Patent US11111270 Publication Date 9/7/2021 |
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More Info.: | Get all data from this article, Assay Method |
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E3 ubiquitin-protein ligase XIAP [265-330] |
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Name: | E3 ubiquitin-protein ligase XIAP [265-330] |
Synonyms: | API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP/ BIR 3 | IAP3 | XIAP | XIAP_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 7652.55 |
Organism: | Homo sapiens (Human) |
Description: | P98170[265-330] |
Residue: | 66 |
Sequence: | YEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWY
PGCKYL
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BDBM518275 |
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n/a |
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Name | BDBM518275 |
Synonyms: | US11111270, Compound 17 |
Type | Small organic molecule |
Emp. Form. | C24H31N5O3 |
Mol. Mass. | 437.5346 |
SMILES | CN[C@@H](C)C(=O)N[C@H]1CCCNC2CCC(N2C1=O)C(=O)Nc1cccc2ccccc12 |r,w:12.11,19.20| |
Structure |
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