| Reaction Details |
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 | Report a problem with these data |
| Target | E3 ubiquitin-protein ligase XIAP [265-330] |
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| Ligand | BDBM518307 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biological Assay |
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| Ki | >50000±n/a nM |
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| Citation |  Cosford, ND; Vamos, MD Inhibitor of apoptosis protein (IAP) antagonists US Patent US11111270 Publication Date 9/7/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| E3 ubiquitin-protein ligase XIAP [265-330] |
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| Name: | E3 ubiquitin-protein ligase XIAP [265-330] |
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| Synonyms: | API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP/ BIR 3 | IAP3 | XIAP | XIAP_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 7652.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P98170[265-330] |
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| Residue: | 66 |
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| Sequence: | YEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWY
PGCKYL
|
|
|
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| BDBM518307 |
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| n/a |
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| Name | BDBM518307 |
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| Synonyms: | US11111270, Compound 28 | US11111270, Compound 29 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H33N5O3 |
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| Mol. Mass. | 427.5398 |
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| SMILES | CN[C@@H](C)C(=O)N[C@H]1CCN[C@H]2CCC(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12 |r,w:14.19| |
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| Structure | 
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