| Reaction Details |
|---|
 | Report a problem with these data |
| Target | E-selectin |
|---|
| Ligand | BDBM528667 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Binding Assay |
|---|
| IC50 | 106±n/a nM |
|---|
| Citation |  Magnani, JL; Peterson, JM; Sarkar, AK; Vohra, YU; Baek, M Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists US Patent US11197877 Publication Date 12/14/2021 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| E-selectin |
|---|
| Name: | E-selectin |
|---|
| Synonyms: | ELAM1 | LYAM2_HUMAN | SELE | Selectin | Selectin E |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 66642.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1438995 |
|---|
| Residue: | 610 |
|---|
| Sequence: | MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLN
SILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREK
DVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNC
TALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVV
ECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK
AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIP
VCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDN
EKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ
WTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHW
SGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESD
GSYQKPSYIL
|
|
|
|---|
| BDBM528667 |
|---|
| n/a |
|---|
| Name | BDBM528667 |
|---|
| Synonyms: | US11197877, Compound 43 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C45H75N4Na4O30S3 |
|---|
| Mol. Mass. | 1340.24 |
|---|
| SMILES | CCC1CC(C[C@@H](O[C@@H]2O[C@@H](CO)[C@H](O)C(O[C@@H](CC3CCCCC3)C(=O)O[Na])C2NC(C)=O)[C@@H]1O[C@@H]1OC(C)[C@@H](O)[C@H](O)C1O)C(=O)NCCNC(=O)CCOCCOCCNC(=O)[C@@H](OS(=O)(=O)O[Na])[C@@H](COS(=O)(=O)O[Na])[Na]OS(O)(=O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
