| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM489605 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radiolabel Binding Studies for Serotonin 5-HT7 Receptors |
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| IC50 | 8.90±n/a nM |
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| Citation |  Blass, BE; Canney, DJ; Blattner, KM 5-hydroxytryptamine receptor 7 modulators and their use as therapeutic agents US Patent US11220505 Publication Date 1/11/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM489605 |
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| n/a |
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| Name | BDBM489605 |
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| Synonyms: | US10961249, Entry 16 | US11220505, Entry 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H31N3O2 |
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| Mol. Mass. | 381.5111 |
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| SMILES | CCC1(CC)CC(CCN2CC3CN(CC3C2)c2ccccc2C#N)OC1=O |
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| Structure | 
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