| Reaction Details |
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 | Report a problem with these data |
| Target | Heat shock protein 90 homolog |
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| Ligand | BDBM551818 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FP-based equilibrium competition assay |
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| EC50 | 398±n/a nM |
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| Citation |  Brown, LE; Huang, DS; Cowen, LE; Whitesell, L; Marcyk, P Hsp90 inhibitors and uses thereof US Patent US11312722 Publication Date 4/26/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Heat shock protein 90 homolog |
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| Name: | Heat shock protein 90 homolog |
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| Synonyms: | HSP90 | HSP90_CANAL |
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| Type: | Protein |
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| Mol. Mass.: | 80784.12 |
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| Organism: | Yeast |
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| Description: | P46598 |
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| Residue: | 707 |
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| Sequence: | MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLE
SEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMI
GQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFL
KEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLE
EVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDP
LAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLS
FIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSK
NIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVE
KSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKE
IKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTM
SSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSN
FAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
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| BDBM551818 |
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| n/a |
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| Name | BDBM551818 |
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| Synonyms: | US11312722, Compound 108 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22N6O3 |
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| Mol. Mass. | 430.4592 |
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| SMILES | Cc1ccccc1-c1cc(Nc2cc(O)cc(O)c2C(=O)N2Cc3cn[nH]c3C2)n(C)n1 |
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| Structure | 
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