| Reaction Details |
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 | Report a problem with these data |
| Target | Transthyretin |
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| Ligand | BDBM50017846 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Binding Assay |
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| IC50 | 741±n/a nM |
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| Citation |  Graef, IA; Alhamadsheh, MM Identification of stabilizers of multimeric proteins US Patent US11337935 Publication Date 5/24/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Transthyretin |
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| Name: | Transthyretin |
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| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 15884.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P02766 |
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| Residue: | 147 |
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| Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
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| BDBM50017846 |
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| n/a |
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| Name | BDBM50017846 |
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| Synonyms: | 3,5-DINITROCATECHOL | 3,5-Dinitro-benzene-1,2-diol | CHEMBL168276 | US10278929, 3,5-dinitrocatecol | US11337935, 3,5-dinitrocatechol |
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| Type | Small organic molecule |
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| Emp. Form. | C6H4N2O6 |
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| Mol. Mass. | 200.1058 |
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| SMILES | Oc1cc(cc(c1O)[N+]([O-])=O)[N+]([O-])=O |
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| Structure | 
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