| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 1 |
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| Ligand | BDBM557831 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | LPAR1 Membrane Binding Assay |
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| Ki | 28.0±n/a nM |
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| Citation |  Ma, T; Wu, L; Zhang, X Lysophosphatidic acid receptor 1 (LPAR1) inhibitor compounds US Patent US11365185 Publication Date 6/21/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 1 |
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| Name: | Lysophosphatidic acid receptor 1 |
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| Synonyms: | EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41120.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92633 |
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| Residue: | 364 |
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| Sequence: | MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
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| BDBM557831 |
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| n/a |
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| Name | BDBM557831 |
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| Synonyms: | 1-[4-[6-[5-[[6-(1-fluoro-1-methyl-ethyl)pyrazin-2-yl]amino]-1-methyl-pyrazol-4-yl]-3-pyridyl]phenyl]cyclopropanecarboxylic Acid; Hydrochloride | US11365185, Example 13B |
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| Type | Small organic molecule |
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| Emp. Form. | C26H25FN6O2 |
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| Mol. Mass. | 472.5141 |
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| SMILES | Cn1ncc(c1Nc1cncc(n1)C(C)(C)F)-c1ccc(cn1)-c1ccc(cc1)C1(CC1)C(O)=O |
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| Structure | 
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