Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orexin receptor type 2 | ||
| Ligand | BDBM559670 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | IP-One Assay | ||
| IC50 | 0.10±n/a nM | ||
| Citation |  L., BS; Ping, C; James, CD; Jian, L; T., RM; Li, X; Dexi, Y; Shishi, L 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS WIPOWO2022109117 Publication Date 5/27/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orexin receptor type 2 | |||
| Name: | Orexin receptor type 2 | ||
| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
| Type: | Protein | ||
| Mol. Mass.: | 50710.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O43614 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM559670 | |||
| n/a | |||
| Name | BDBM559670 | ||
| Synonyms: | WO2022109117, Example 15 | WO2022109117, Example 17 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H35N3O6S | ||
| Mol. Mass. | 481.606 | ||
| SMILES | C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(OCCOC(=O)N12)c3 |wU:14.14,17.16,wD:1.0,3.3,11.33,(16.49,5.93,;16.12,4.46,;17.09,3.29,;16.28,2.01,;16.85,.6,;18.35,.38,;18.57,1.88,;18.13,-1.12,;19.85,.16,;20.41,-1.25,;20.79,1.36,;14.81,2.38,;14.33,.88,;13.29,-.35,;11.68,-.68,;10.35,-1.51,;8.92,-.93,;8.71,.62,;10,1.46,;11.38,.83,;7.6,1.81,;6.04,1.9,;5.32,3.25,;6.06,4.57,;7.61,4.53,;8.49,5.8,;9.79,6.63,;11.33,6.8,;12.81,6.34,;14,5.33,;15.2,6.26,;14.71,3.89,;8.34,3.17,)| | ||
| Structure | 
| ||