Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orexin receptor type 2 | ||
| Ligand | BDBM559731 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | IP-One Assay | ||
| IC50 | 0.41±n/a nM | ||
| Citation |  L., BS; Ping, C; James, CD; Jian, L; T., RM; Li, X; Dexi, Y; Shishi, L 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS WIPOWO2022109117 Publication Date 5/27/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orexin receptor type 2 | |||
| Name: | Orexin receptor type 2 | ||
| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
| Type: | Protein | ||
| Mol. Mass.: | 50710.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O43614 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM559731 | |||
| n/a | |||
| Name | BDBM559731 | ||
| Synonyms: | WO2022109117, Example 76 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H35N3O7S | ||
| Mol. Mass. | 497.605 | ||
| SMILES | COc1ccc2nc1OCCCOC(=O)N1[C@H](C)C[C@H](NS(C)(=O)=O)[C@@H]1COC1CCC2CC1 |wD:16.17,19.20,25.26,(1.65,5.58,;3.17,5.74,;4.07,4.52,;3.42,3.13,;4.33,1.89,;5.9,1.98,;6.46,3.43,;5.6,4.72,;6.31,6.12,;7.46,7.16,;8.93,7.6,;10.47,7.46,;11.85,6.76,;12.89,5.59,;14.2,6.35,;13.41,4.06,;14.86,4.5,;15.37,5.94,;15.73,3.25,;14.81,2.04,;15.24,.58,;16.72,.22,;18.2,-.13,;17.07,1.71,;16.37,-1.26,;13.37,2.54,;12.76,1.09,;11.61,.01,;10.06,-.28,;9.79,1.24,;8.37,1.78,;7.11,.89,;7.4,-.66,;8.82,-1.24,)| | ||
| Structure | 
| ||