| Reaction Details |
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 | Report a problem with these data |
| Target | Stimulator of interferon genes protein [139-328] |
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| Ligand | BDBM564858 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radiometric Filtration Binding Competition Assay |
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| IC50 | <10000±n/a nM |
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| Citation |  Chamberlain, BT; Rice, JM; Jernigan, III, FE; Sherman, W; Kulkarni, MM; Shechter, S; Allen, BK; Tan, D; Marino, KA; Lin, Z Oxoacridinyl acetic acid derivatives and methods of use US Patent US11414387 Publication Date 8/16/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Stimulator of interferon genes protein [139-328] |
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| Name: | Stimulator of interferon genes protein [139-328] |
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| Synonyms: | Eris | Mita | Mpys | STING_MOUSE | Stimulator of interferon genes protein (STING)(139-328) | Sting | Sting1 | Tmem173 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 21484.24 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | aa 139-328 |
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| Residue: | 190 |
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| Sequence: | TPAEVSAVCEEKKLNVAHGLAWSYYIGYLRLILPGLQARIRMFNQLHNNMLSGAGSRRLY
ILFPLDCGVPDNLSVVDPNIRFRDMLPQQNIDRAGIKNRVYSNSVYEILENGQPAGVCIL
EYATPLQTLFAMSQDAKAGFSREDRLEQAKLFCRTLEEILEDVPESRNNCRLIVYQEPTD
GNSFSLSQEV
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| BDBM564858 |
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| n/a |
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| Name | BDBM564858 |
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| Synonyms: | US11414387, Compound 12 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12ClNO3 |
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| Mol. Mass. | 301.724 |
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| SMILES | Cc1ccc2c(c1)n(CC(O)=O)c1c(Cl)cccc1c2=O |
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| Structure | 
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