| Reaction Details |
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 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 7 |
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| Ligand | BDBM564968 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Pharmacology |
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| IC50 | <500±n/a nM |
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| Citation |  Duvey, G; Celanire, S Heterocyclic compounds as modulators of mGluR7 US Patent US11414395 Publication Date 8/16/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Metabotropic glutamate receptor 7 |
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| Name: | Metabotropic glutamate receptor 7 |
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| Synonyms: | GPRC1G | GRM7 | GRM7 protein | GRM7_HUMAN | MGLUR7 | Metabotropic glutamate receptor 7 | metabotropic glutamate 7 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 102262.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q14831 |
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| Residue: | 915 |
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| Sequence: | MVQLRKLLRVLTLMKFPCCVLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAK
GPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSL
TFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYA
STAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQ
ISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAK
RADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRR
NVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAH
ALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIF
QYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTP
CCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAML
GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRV
FLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIW
FGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGV
PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGML
YMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNS
PAAKKKYVSYNNLVI
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| BDBM564968 |
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| n/a |
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| Name | BDBM564968 |
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| Synonyms: | US11414395, Example 15 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23N3O2 |
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| Mol. Mass. | 361.4369 |
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| SMILES | COc1ccnc(c1)-n1ncc2CC(CCc2c1=O)c1ccc(C)cc1C |
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| Structure | 
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