| Reaction Details |
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 | Report a problem with these data |
| Target | Luciferin 4-monooxygenase |
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| Ligand | BDBM566483 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dual-Glo Luciferase Assay |
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| IC50 | <100±n/a nM |
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| Citation |  Konradi, AW; Lin, TT Bicyclic compounds US Patent US11420935 Publication Date 8/23/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Luciferin 4-monooxygenase |
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| Name: | Luciferin 4-monooxygenase |
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| Synonyms: | LUCI_LUCMI | Luciferase |
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| Type: | Protein |
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| Mol. Mass.: | 60495.67 |
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| Organism: | Southern Russian firefly |
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| Description: | Q26304 |
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| Residue: | 548 |
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| Sequence: | MEMEKEENVVYGPLPFYPIEEGSAGIQLHKYMHQYAKLGAIAFSNALTGVDISYQEYFDI
TCRLAEAMKNFGMKPEEHIALCSENCEEFFIPVLAGLYIGVAVAPTNEIYTLRELNHSLG
IAQPTIVFSSRKGLPKVLEVQKTVTCIKKIVILDSKVNFGGHDCMETFIKKHVELGFQPS
SFVPIDVKNRKQHVALLMNSSGSTGLPKGVRITHEGAVTRFSHAKDPIYGNQVSPGTAIL
TVVPFHHGFGMFTTLGYFACGYRVVMLTKFDEELFLRTLQDYKCTSVILVPTLFAILNKS
ELIDKFDLSNLTEIASGGAPLAKEVGEAVARRFNLPGVRQGYGLTETTSAFIITPEGDDK
PGASGKVVPLFKVKVIDLDTKKTLGVNRRGEICVKGPSLMLGYSNNPEATRETIDEEGWL
HTGDIGYYDEDEHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPDAG
ELPGAVVVMEKGKTMTEKEIVDYVNSQVVNHKRLRGGVRFVDEVPKGLTGKIDAKVIREI
LKKPQAKM
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|
|
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| BDBM566483 |
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| n/a |
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| Name | BDBM566483 |
|---|
| Synonyms: | N-(cyanomethyl)-5-(4- (trifluoromethyl)phenoxy)-2- naphthamid | US11420935, Compound 22 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H13F3N2O2 |
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| Mol. Mass. | 370.3246 |
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| SMILES | FC(F)(F)c1ccc(Oc2cccc3cc(ccc23)C(=O)NCC#N)cc1 |
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| Structure | 
|
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