| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
|---|
| Ligand | BDBM458591 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Binding Affinity Assay |
|---|
| Ki | 0.150±n/a nM |
|---|
| Citation |  Yoshinaga, H; Ikuma, Y; Ikeda, J; Adachi, S; Mitsunuma, H; Aihara, Y; Besnard, J; Bell, AS Substituted lactams showing serotonin 5-HT receptor activity US Patent US11466007 Publication Date 10/11/2022 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2A |
|---|
| Name: | 5-hydroxytryptamine receptor 2A |
|---|
| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
|---|
| Type: | undefined |
|---|
| Mol. Mass.: | 52607.65 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P28223 |
|---|
| Residue: | 471 |
|---|
| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
|
|
|
|---|
| BDBM458591 |
|---|
| n/a |
|---|
| Name | BDBM458591 |
|---|
| Synonyms: | US10745401, Example 65 | US11466007, Example 65 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H26N6OS |
|---|
| Mol. Mass. | 410.536 |
|---|
| SMILES | Cc1c2c(CCN(CCN3CCN(CC3)c3nsc4ccccc34)C2=O)nn1C |
|---|
| Structure | 
|
|---|
Search and Browse
