| Reaction Details |
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 | Report a problem with these data |
| Target | External core antigen |
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| Ligand | BDBM576388 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PHH Natural Infection Assay |
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| IC50 | 177±n/a nM |
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| Citation |  Xianfeng, L; Hongying, Y; Bo, Z; Xiufang, Z AROMATIC SPIRO RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION WIPOWO2022112207 Publication Date 6/2/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| External core antigen |
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| Name: | External core antigen |
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| Synonyms: | C | HBEAG_HBVGB | HBeAg | Precore protein | p25 |
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| Type: | Protein |
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| Mol. Mass.: | 24103.68 |
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| Organism: | HBVgbn |
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| Description: | P89951 |
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| Residue: | 212 |
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| Sequence: | MQLFHLCLIISCSCPTVQASKLCLGWLLGMDIDPYKEFGASVELLSFLPSDFFPSVRDLL
DTASALYREALESPEHCSPNHTALRQAVLCWGELMTGCSWVGNNLEDPASRELVVNYVNT
NMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRR
RGRSPRRRTPSPRRRRSQSPRRRRSQSPASQC
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| BDBM576388 |
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| n/a |
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| Name | BDBM576388 |
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| Synonyms: | N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3.3]heptan-2-yl]-5-cyclopropylsulfonyl-furan-2-carboxamide | WO2022112207, Example 17 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21ClN2O5S |
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| Mol. Mass. | 460.931 |
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| SMILES | n/a |
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| Structure | 
|
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