| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metallo-beta-lactamase VIM-2 |
|---|
| Ligand | BDBM21642 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Single Dose Enzymatic Inhibition Assay |
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| Ki | 630±n/a nM |
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| Citation |  Sham, YY; Muthyala, R; Shin, W Therapeutic methods and combinations US Patent US11491146 Publication Date 11/8/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Metallo-beta-lactamase VIM-2 |
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| Name: | Metallo-beta-lactamase VIM-2 |
|---|
| Synonyms: | Beta-lactamase VIM-2 | Metallo-beta-lactamase VIM-2 (VIM-2) |
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| Type: | Protein |
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| Mol. Mass.: | 28318.00 |
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| Organism: | Pseudomonas aeruginosa (g-Proteobacteria) |
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| Description: | n/a |
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| Residue: | 266 |
|---|
| Sequence: | MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQ
SFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRV
GGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHS
TDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGH
GLPGGLDLLKHTTNVVKAHTNRSVVE
|
|
|
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| BDBM21642 |
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| n/a |
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| Name | BDBM21642 |
|---|
| Synonyms: | (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid | CHEMBL1560 | Capozide | Captopril | Lopirin | SQ 14,225 | SQ14534 | US11491146, Compound L-Captopril |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H15NO3S |
|---|
| Mol. Mass. | 217.285 |
|---|
| SMILES | C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O |
|---|
| Structure | 
|
|---|
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