| Reaction Details |
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 | Report a problem with these data |
| Target | Histone acetyltransferase KAT5 |
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| Ligand | BDBM580668 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kat5 Assay |
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| Ki | 1710±n/a nM |
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| Citation |  Bozikis, YE; Camerino, MA; Kung, P; Stupple, PA; Sutton, SC Benzisoxazole sulfonamide derivatives US Patent US11492346 Publication Date 11/8/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone acetyltransferase KAT5 |
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| Name: | Histone acetyltransferase KAT5 |
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| Synonyms: | HTATIP | KAT5 | KAT5_HUMAN | TIP60 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58595.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_796787 |
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| Residue: | 513 |
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| Sequence: | MAEVGEIIEGCRLPVLRRNQDNEDEWPLAEILSVKDISGRKLFYVHYIDFNKRLDEWVTH
ERLDLKKIQFPKKEAKTPTKNGLPGSRPGSPEREVPASAQASGKTLPIPVQITLRFNLPK
EREAIPGGEPDQPLSSSSCLQPNHRSTKRKVEVVSPATPVPSETAPASVFPQNGAARRAV
AAQPGRKRKSNCLGTDEDSQDSSDGIPSAPRMTGSLVSDRSHDDIVTRMKNIECIELGRH
RLKPWYFSPYPQELTTLPVLYLCEFCLKYGRSLKCLQRHLTKCDLRHPPGNEIYRKGTIS
FFEIDGRKNKSYSQNLCLLAKCFLDHKTLYYDTDPFLFYVMTEYDCKGFHIVGYFSKEKE
STEDYNVACILTLPPYQRRGYGKLLIEFSYELSKVEGKTGTPEKPLSDLGLLSYRSYWSQ
TILEILMGLKSESGERPQITINEISEITSIKKEDVISTLQYLNLINYYKGQYILTLSEDI
VDGHERAMLKRLLRIDSKCLHFTPKDWSKRGKW
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|
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| BDBM580668 |
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| n/a |
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| Name | BDBM580668 |
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| Synonyms: | US11492346, Example 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H19BrN4O6S |
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| Mol. Mass. | 523.357 |
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| SMILES | COc1cc(Br)cc(OC)c1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12 |
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| Structure | 
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