| Reaction Details |
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 | Report a problem with these data |
| Target | 2-Hydroxyacid oxidase 1 |
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| Ligand | BDBM581148 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In-Vitro Human Glycolate Oxidase (hGOX) Assay |
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| IC50 | 1.000±n/a nM |
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| Citation |  Kabakibi, A; Kahraman, M; Clare, M; Leedom, T Compounds and methods for treating oxalate-related diseases US Patent US11504367 Publication Date 11/22/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| 2-Hydroxyacid oxidase 1 |
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| Name: | 2-Hydroxyacid oxidase 1 |
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| Synonyms: | GOX1 | HAO1 | HAOX1_HUMAN | Hydroxyacid oxidase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40927.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_71275 |
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| Residue: | 370 |
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| Sequence: | MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET
DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE
AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ
LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR
GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV
LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV
RKNPLAVSKI
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| BDBM581148 |
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| n/a |
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| Name | BDBM581148 |
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| Synonyms: | 5-(3-((3- chlorophenyl)ethynyl)phenoxy)- 1H-1,2,3-triazole-4- carboxylic acid | US11504367, Example 187 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H10ClN3O3 |
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| Mol. Mass. | 339.733 |
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| SMILES | OC(=O)c1nn[nH]c1Oc1cccc(c1)C#Cc1cccc(Cl)c1 |
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| Structure | 
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