| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ubiquitin carboxyl-terminal hydrolase 7 |
|---|
| Ligand | BDBM581908 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | USP7 assay |
|---|
| IC50 | <20±n/a nM |
|---|
| Citation |  Sara, B; Xiaoxi, L; Sara, B; Xiaoxi, L INHIBITORS TARGETING UBIQUITIN SPECIFIC PROTEASE 7 (USP7) WIPOWO2023003973 Publication Date 1/26/2023 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ubiquitin carboxyl-terminal hydrolase 7 |
|---|
| Name: | Ubiquitin carboxyl-terminal hydrolase 7 |
|---|
| Synonyms: | Deubiquitinating enzyme 7 | HAUSP | Herpesvirus-associated ubiquitin-specific protease | UBP7_HUMAN | USP7 | Ubiquitin thioesterase 7 | Ubiquitin-specific-processing protease 7 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 128274.45 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1469483 |
|---|
| Residue: | 1102 |
|---|
| Sequence: | MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDME
DDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQ
CNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPE
KGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRK
AVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELC
RVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNI
FESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIK
INDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKF
DDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQL
VERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS
SLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTI
FLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVM
CDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSEL
PTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFF
KSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLN
SQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLE
CLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREV
MKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLD
HFNKAPKRSRYTYLEKAIKIHN
|
|
|
|---|
| BDBM581908 |
|---|
| n/a |
|---|
| Name | BDBM581908 |
|---|
| Synonyms: | WO2023003973, Compound 108 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C47H57ClN8O5 |
|---|
| Mol. Mass. | 849.459 |
|---|
| SMILES | CC(C)c1cnc2cc(ccc2c1Cl)C(=O)NCCN1CCC(C(C1)c1ccccc1)C(=O)N1CCC(O)(Cn2cnc3cc(OCCN4CCNCC4)ccc3c2=O)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
